Ontology highlight
ABSTRACT:
SUBMITTER: Sambo F
PROVIDER: S-EPMC6162885 | biostudies-other | 2018 Sep
REPOSITORIES: biostudies-other
BMC bioinformatics 20180929 1
<h4>Background</h4>Targeted amplicon sequencing of the 16S ribosomal RNA gene is one of the key tools for studying microbial diversity. The accuracy of this approach strongly depends on the choice of primer pairs and, in particular, on the balance between efficiency, specificity and sensitivity in the amplification of the different bacterial 16S sequences contained in a sample. There is thus the need for computational methods to design optimal bacterial 16S primers able to take into account the ...[more]