Ontology highlight
ABSTRACT:
SUBMITTER: Kovacs IA
PROVIDER: S-EPMC6423278 | biostudies-other | 2019 Mar
REPOSITORIES: biostudies-other
Nature communications 20190318 1
Despite exceptional experimental efforts to map out the human interactome, the continued data incompleteness limits our ability to understand the molecular roots of human disease. Computational tools offer a promising alternative, helping identify biologically significant, yet unmapped protein-protein interactions (PPIs). While link prediction methods connect proteins on the basis of biological or network-based similarity, interacting proteins are not necessarily similar and similar proteins do ...[more]