Ontology highlight
ABSTRACT:
SUBMITTER: Castellani S
PROVIDER: S-EPMC6736848 | biostudies-other | 2019 Sep
REPOSITORIES: biostudies-other
Castellani Stefano S D'Oria Susanna S Diana Anna A Polizzi Angela Maria AM Di Gioia Sante S Mariggiò Maria Addolorata MA Guerra Lorenzo L Favia Maria M Vinella Angela A Leonetti Giuseppina G De Venuto Domenica D Gallo Crescenzio C Montemurro Pasqualina P Conese Massimo M
Scientific reports 20190910 1
The role of colony stimulating factors (CSFs) in cystic fibrosis (CF) circulating neutrophils has not been thoroughly evaluated, considering that the neutrophil burden of lung inflammation in these subjects is very high. The aim of this study was to assess granulocyte-CSF (G-CSF) and granulocyte-macrophage-CSF (GM-CSF) levels in CF patients in various clinical conditions and how these cytokines impact on activation and priming of neutrophils. G-CSF and GM-CSF levels were measured in sputum and s ...[more]