Ontology highlight
ABSTRACT:
SUBMITTER: Zuo Y
PROVIDER: S-EPMC6817565 | biostudies-other | 2019
REPOSITORIES: biostudies-other
Frontiers in genetics 20191022
Prostate cancer remains the second leading cause of male cancer death, and there is an unmet need for biomarkers to identify patients with such aggressive disease. Piwi-inteacting RNAs (piRNAs) have been classified as transcriptional and posttranscriptional regulators in somatic cells. In this study, we discovered three piRNAs as novel prognostic markers and their association with prostate cancer biochemical recurrence was confirmed in validation data set. To obtain a better understanding of piR ...[more]