ARGONAUTE10 controls cell fate specification and formative cell divisions in the Arabidopsis root

ABSTRACT: A key question in plant biology is how oriented cell divisions are integrated with patterning mechanisms to generate organs with adequate cell type allocation. In the root vasculature, a gradient of miRNA165/6 controls the abundance of HD-ZIP III transcription factors, which in turn control cell fate and spatially restrict vascular cell proliferation to specific cells. Here, we show that vascular development requires the presence of ARGONAUTE10, which is thought to sequester miRNA165/6 and protect HD-ZIP III transcripts from degradation. Our results suggest that the miR165/6-AGO10-HDZIP III module acts by buffering cytokinin responses and restricting xylem differentiation. Mutants of AGO10 show faster growth rates and strongly enhanced survival under severe drought conditions. However, thi

SUBMITTER: Nabila El Arbi 

PROVIDER: S-SCDT-10_1038-S44318-024-00072-X | biostudies-other |

REPOSITORIES: biostudies-other