LimbNET: collaborative platform for simulating spatial patterns of gene networks in limb development

ABSTRACT: Successful computational modelling of complex biological phenomena will depend on the seamless sharing of models and hypotheses between researchers of all backgrounds - experimental and theoretical. LimbNET, a new online tool for modelling, simulating and visualising spatiotemporal patterning in limb development, aims to facilitate this process within the limb development community. LimbNET enables remote users to define and simulate arbitrary gene regulatory network (GRN) models of 2D spatiotemporal developmental patterning processes. Researchers can test and compare each others' hypotheses within a common framework. A database of previously created models empowers users to simulate, explore, and extend each others' work. Spatiotemporally-varying gene expression intensities, derived from

SUBMITTER: Antoni Matyjaszkiewicz 

PROVIDER: S-SCDT-10_1038-S44320-025-00128-Y | biostudies-other |

REPOSITORIES: biostudies-other