Selective autophagy regulates chloroplast protein import and promotes plant stress tolerance

ABSTRACT: Chloroplasts are plant organelles responsible for photosynthesis and environmental sensing. Most chloroplast proteins are imported from the cytosol through the translocon at the outer envelope membrane of chloroplasts (TOC). Previous work has shown that TOC components are regulated by the ubiquitin-proteasome system (UPS) to control the chloroplast proteome, which is crucial for the organelle's function and plant development. Here, we demonstrate that the TOC apparatus is also subject to K63-linked polyubiquitination and regulation by selective autophagy, potentially to promote plant stress tolerance. We identify NBR1 as a selective autophagy adaptor targeting TOC components, and mediating their relocation into vacuoles for autophagic degradation. Such selective autophagy is shown to contr

SUBMITTER: Dr. Qihua Ling 

PROVIDER: S-SCDT-10_15252-EMBJ_2022112534 | biostudies-other |

REPOSITORIES: biostudies-other