The tyrosine phosphorylation of the lectin receptor-like kinase LORE regulates plant immunity

ABSTRACT: Plant pattern recognition receptors (PRRs) perceive pathogen-associated molecular patterns (PAMPs) to activate immune responses. Medium-chain 3-hydroxy fatty acids (mc-3-OH-FAs), which are widely present in Gram-negative bacteria, were recently shown to be novel PAMPs in Arabidopsis thaliana. The Arabidopsis PRR LORE is a G-type lectin receptor-like kinase that recognizes mc-3-OH-FAs and subsequently mounts an immune response; however, the mechanisms underlying LORE activation and downstream signaling are unexplored. Here, we report that one of the mc-3-OH-FAs, 3-OH-C10:0, induces the phosphorylation of LORE at tyrosine residue 600 (Y600). The phosphorylated LORE trans-phosphorylates the downstream receptor-like cytoplasmic kinase PBL34 and its close paralogs, PBL35 and PBL36, and thereby

SUBMITTER: Dr. Jun Liu 

PROVIDER: S-SCDT-EMBOJ-2019-102856 | biostudies-other |

REPOSITORIES: biostudies-other