Barley stripe mosaic virus γb protein disrupts chloroplast antioxidant defenses to optimize viral replication

ABSTRACT: The plant antioxidant system plays important roles in response to diverse abiotic and biotic stresses. However, the effects of virus infection on host redox homeostasis and how antioxidant defense pathway are manipulated by viruses remain poorly understood. We previously verified that the γb protein is recruited to the chloroplast by the viral αa replicase to enhance Barley stripe mosaic virus (BSMV) replication. Here, we extend this study by demonstrating that BSMV infection induces chloroplast oxidative stress. The versatile γb protein interacts directly with NADPH-dependent thioredoxin reductase C (NTRC), a core component of chloroplast antioxidant systems. Overexpression of NbNTRC significantly impairs BSMV replication in Nicotiana benthamiana plants, whereas disruption of NbNTRC expre

SUBMITTER: Mrs. Xueting Wang 

PROVIDER: S-SCDT-EMBOJ-2021-107660P | biostudies-other |

REPOSITORIES: biostudies-other