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Genome-wide binding map of FoxO1 and Pax5 in pre-B cells


ABSTRACT: Genome-wide analysis of FoxO1 and Pax5 binding in pre-B cells following attenuation of IL-7 signaling. Transcription factor FoxO1 has been shown to be an essential factor for Ig light chain rearrangement. Results demonstrate that FoxO1 and Pax5 co-target genes that are activated during pre-B cell differentiation. Examination of FoxO1 and/or Pax5 binding under withdrawal of IL-7R signaling.

ORGANISM(S): Mus musculus

PROVIDER: E-GEOD-35024 | BioStudies |

REPOSITORIES: biostudies

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