Unknown

Dataset Information

0

Differentially expressed genes between oncogene-transformed and non-transformed fetal liver progenitor cells


ABSTRACT: The activation of different oncogenic signals may primarily contribute to the heterogeneity of cancer cells. However, the exact mechanisms underlying different oncogenic transformation are still unclear. We used the c-Myc, H-Ras and Akt transformed liver cell model to define mRNA expression profiles in the non-transformed and the three types of oncogene-transformed cells Purified p53-/- mouse fetal liver progenitor cells were transformed by three oncogenic genetic factors, c-Myc, H-RasV12 and myristoylated-AKT1(myr-Akt). The gene expression profilings of transformed cells and control cells were analyzed through microarray.

ORGANISM(S): Mus musculus

PROVIDER: E-GEOD-43991 | BioStudies |

REPOSITORIES: biostudies

Similar Datasets

2013-02-02 | E-GEOD-43991 | ArrayExpress
| S-EPMC7080752 | BioStudies
2015-01-01 | S-EPMC4385847 | BioStudies
| S-EPMC8405961 | BioStudies
| S-EPMC5345014 | BioStudies
| S-EPMC5746102 | BioStudies
| S-EPMC5794774 | BioStudies
| E-GEOD-6505 | BioStudies
2008-06-12 | E-GEOD-2516 | ArrayExpress
| S-EPMC5658677 | BioStudies