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Probing In vivo Brachyury Function with Tc mouse model


ABSTRACT: To identify Brachyury target genes in vivo and elucidate how Brachyury-mediated regulation contributes to early mouse developmental homeostasis and coordination, we performed mRNA-seq to compare gene expression profiles of WT and Tc/Tc embryos at both E7.5 ~ 8.0 and E10.0 ~ 10.5 WT and Tc/Tc embryos were isolated at both E7.5 ~ 8.0 and E10.0 ~ 10.5. Subsequently, directional mRNA-seq expriments were performed with wild-type and Tc/Tc whole embryos

ORGANISM(S): Mus musculus

PROVIDER: E-GEOD-54982 | BioStudies |

REPOSITORIES: biostudies

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