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Transcription profiling of human mantle cell lymphoma cell lines with inhibition of the NMD pathway


ABSTRACT: Identification of potential tumor suppressor genes using the GINI strategy in Mantle Cell Lymphoma cell lines Experiment Overall Design: Inhibition of the NMD pathway was performed in Mantle Cell Lymphoma cell lines according to a modified protocol previously described (Noensie EN et al Nat Biotechnol 2001;19:434-439; Huusko P et al, Nat Gentet 2004; 36:979-983). The cells were treated with emetine or with emetine followed by incubation with actinomycin D during a time course. Mock treated cells were used as reference.

ORGANISM(S): Homo sapiens

PROVIDER: E-GEOD-6728 | BioStudies |

REPOSITORIES: biostudies