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Transcription profiling by array of human dendritic cells after treatment with TNFalpha, IL1b, IL6 and PGE2


ABSTRACT: Day 6 human monocyte derived dendritic cells were left unstimulated or matured for 2 days using the golden standard maturation cocktail currently used in clinical practice. Maturation induced changes in mRNA expression were determined by calculation of expression in mature DC relative to immature DC. Obtained gene expression raito's were compared to protein expression ratio's from the same batch of cells at the pathway level (proteomics data of this experiment is deposited in Human Proteinpedia, accession number pending).

ORGANISM(S): Homo sapiens

PROVIDER: E-MEXP-2290 | BioStudies |

REPOSITORIES: biostudies

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