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Transcription profiling of C. elegans after infection with Microbacterium nematophilum


ABSTRACT: Genomic response of C. elegans after infection with Microbacterium nematophilum.

The interaction between the nematode Caenorhabditis elegans and a Gram-positive bacterial pathogen, Microbacterium nematophilum, provides a model for an innate immune response in nematodes. This pathogen adheres to the rectal and post-anal cuticle of the worm, causing slowed growth, constipation, and a defensive swelling response of rectal hypodermal cells. To explore the genomic responses that the worm activates after pathogenic attack we used microarray analysis of transcriptional changes induced after 6 hr infection, comparing virulent with avirulent infection.

ORGANISM(S): Caenorhabditis elegans

PROVIDER: E-MEXP-696 | BioStudies |

REPOSITORIES: biostudies

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