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Fixation of the first component of complement by immune complexes: effect of reduction and fragmentation of antibody.


ABSTRACT: The integrity of both covalent and non-covalent bonds between the heavy chains of rabbit immunoglobulin gamma antibody is essential for maximal efficiency of binding of the first component of complement to immune complexes.

SUBMITTER: Press EM 

PROVIDER: S-EPMC1165615 | BioStudies | 1975-01-01

SECONDARY ACCESSION(S): 10.1042/bj1490285

REPOSITORIES: biostudies

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