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Secrets of insulin and IGF-1 regulation of insulin secretion revealed.


ABSTRACT: There has been ongoing controversy over the respective roles of insulin-like growth factor-1 receptors and insulin receptors in controlling insulin release from beta-cells of the pancreas. An acute knock-down experiment exploiting small interfering RNA approaches provides a resolution: both are required.

SUBMITTER: Shepherd PR 

PROVIDER: S-EPMC1223857 | BioStudies | 2004-01-01

SECONDARY ACCESSION(S): 10.1042/BJ20031747

REPOSITORIES: biostudies

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