Structure of Citrobacter freundii L-methionine gamma-lyase.
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ABSTRACT: L-Methionine gamma-lyase (MGL) is a pyridoxal 5'-phosphate (PLP) dependent enzyme that catalyzes gamma-elimination of L-methionine. The crystal structure of MGL from Citrobacter freundii has been determined at 1.9 A resolution. The spatial fold of the protein is similar to those of MGLs from Pseudomonas putida and Trichomonas vaginalis. The comparison of these structures revealed that there are differences in PLP-binding residues and positioning of the surrounding flexible loops.
SUBMITTER: Mamaeva DV
PROVIDER: S-EPMC1952331 | BioStudies | 2005-01-01
SECONDARY ACCESSION(S): 1y4i
REPOSITORIES: biostudies
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