Unknown

Dataset Information

0

Isoxazoles from 1,1-Disubstituted Bromoalkenes.


ABSTRACT: The regioselective synthesis of 3,5-disubstituted isoxazoles was achieved through the 1,3-dipolar cycloaddition of nitrile oxides with 1,1-disubstituted bromoalkenes. The substituted bromoalkenes function as alkyne synthons which were used to construct 5,5-disubstituted bromoisoxazoline intermediates that aromatize to the analogous isoxazoles through the loss of HBr.

SUBMITTER: Dadiboyena S 

PROVIDER: S-EPMC2031838 | BioStudies | 2007-01-01

REPOSITORIES: biostudies

Similar Datasets

2017-01-01 | S-EPMC5389174 | BioStudies
2011-01-01 | S-EPMC3184321 | BioStudies
2012-01-01 | S-EPMC3601750 | BioStudies
2016-01-01 | S-EPMC5189986 | BioStudies
2012-01-01 | S-EPMC3376396 | BioStudies
1000-01-01 | S-EPMC5748833 | BioStudies
2009-01-01 | S-EPMC6255254 | BioStudies
2006-01-01 | S-EPMC2527062 | BioStudies
2012-01-01 | S-EPMC3601746 | BioStudies
2008-01-01 | S-EPMC3750120 | BioStudies