Dataset Information


Sequencing emm-specific PCR products for routine and accurate typing of group A streptococci.

ABSTRACT: Rapid sequence analysis of specific PCR products was used to accurately deduce emm types corresponding to the majority of the known group A streptococcal (GAS) M serotypes. The study involved 95 M type reference GAS strains and a survey of 74 recent clinical isolates. A high percentage of agreement between M type serology and the previously published 5' sequences of the emm genes of M type reference strains was noted. The 5' sequences for six established M protein genes--the emm-32, emm-34, emm-38, emm-40, emm-42, and emm-71 genes--were determined to supplement the existing emm sequence database. Rapid sequence analysis differentiated serologically M-nontypeable strains and was used to establish the probable.

PROVIDER: S-EPMC228924 | BioStudies | 1996-01-01T00:00:00Z

REPOSITORIES: biostudies

Similar Datasets

| S-EPMC3296615 | BioStudies
1999-01-01 | S-EPMC2640698 | BioStudies
| S-EPMC1234087 | BioStudies
1997-01-01 | S-EPMC232734 | BioStudies
| S-EPMC1081262 | BioStudies
| S-EPMC6321872 | BioStudies
| S-EPMC88333 | BioStudies
| S-EPMC4692479 | BioStudies
| S-EPMC6927302 | BioStudies
| S-EPMC5478724 | BioStudies