Unknown

Dataset Information

0

Synthesis of barbiturate-based methionine aminopeptidase-1 inhibitors.


ABSTRACT: The syntheses of a new class of barbiturate-based inhibitors for human and Escherichia Coli methionine aminopeptidase-1 (MetAP-1) are described. Some of the synthesized inhibitors show selective inhibition of the human enzyme with high potency.

SUBMITTER: Haldar MK 

PROVIDER: S-EPMC2390822 | BioStudies | 2008-01-01

REPOSITORIES: biostudies

Similar Datasets

2010-01-01 | S-EPMC2860377 | BioStudies
2010-01-01 | S-EPMC2844763 | BioStudies
2009-01-01 | S-EPMC2783975 | BioStudies
2008-01-01 | S-EPMC2737180 | BioStudies
2013-01-01 | S-EPMC3688283 | BioStudies
2010-01-01 | S-EPMC2820511 | BioStudies
2011-01-01 | S-EPMC3098952 | BioStudies
2016-01-01 | S-EPMC5009474 | BioStudies
1000-01-01 | S-EPMC1599997 | BioStudies
2006-01-01 | S-EPMC1480431 | BioStudies