Unknown

Dataset Information

0

Detection of differences in the nucleotide and amino acid sequences of diphtheria toxin from Corynebacterium diphtheriae and Corynebacterium ulcerans causing extrapharyngeal infections.


ABSTRACT: While Corynebacterium ulcerans can mimic classical diphtheria, extrapharyngeal infections are extremely rare. Sequencing of the diphtheria toxin (DT)-encoding tox gene of two C. ulcerans isolates from extrapharyngeal infections revealed differences from C. diphtheriae DT sequences, mainly in the translocation and receptor-binding domains. C. ulcerans supernatants were much less potent than supernatant from C. diphtheriae. A C. ulcerans DT-specific PCR is described below.

SUBMITTER: Sing A 

PROVIDER: S-EPMC254330 | BioStudies | 2003-01-01

REPOSITORIES: biostudies

Similar Datasets

2011-01-01 | S-EPMC3147892 | BioStudies
2012-01-01 | S-EPMC3406963 | BioStudies
2019-01-01 | S-EPMC6359835 | BioStudies
2008-01-01 | S-EPMC2224273 | BioStudies
1000-01-01 | S-EPMC54451 | BioStudies
2012-01-01 | S-EPMC3370855 | BioStudies
2017-01-01 | S-EPMC5176206 | BioStudies
2013-01-01 | S-EPMC4184488 | BioStudies
2019-01-01 | S-EPMC6455118 | BioStudies
2014-01-01 | S-EPMC4313305 | BioStudies