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The ClC-3 Cl-/H+ antiporter becomes uncoupled at low extracellular pH.


ABSTRACT: Adenovirus expressing ClC-3 (Ad-ClC-3) induces Cl(-)/H(+) antiport current (I(ClC-3)) in HEK293 cells. The outward rectification and time dependence of I(ClC-3) closely resemble an endogenous HEK293 cell acid-activated Cl(-) current (ICl(acid)) seen at extracellular pH

SUBMITTER: Matsuda JJ 

PROVIDER: S-EPMC2807314 | BioStudies | 2010-01-01

SECONDARY ACCESSION(S): Q9R279

REPOSITORIES: biostudies

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