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Conjugate addition of lithiated methyl pyridines to enones.

ABSTRACT: Preparatively useful conjugate addition of lithiated methyl pyridines to cyclic and acyclic enones is reported. Addition of 2-picoline to 3-penten-2-one led to a concise synthesis of the alkaloids (+/-)-senepodine G and (+/-)-cermizine C.

SUBMITTER: Taber DF

PROVIDER: S-EPMC2921646 | BioStudies | 2010-01-01

REPOSITORIES: biostudies

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