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3-(4-Chloro-benzo-yl)-4-(4-chloro-phen-yl)-1-phenethyl-piperidin-4-ol.


ABSTRACT: In the title compound, C(26)H(25)Cl(2)NO(2), the piperidine ring adopts a chair conformation with a cis configuration of the carbonyl and hy-droxy substituents. The dihedral angle between the aromatic rings of the chloro-benzene groups is 24.3?(2)°. The phenyl ring forms dihedral angles of 59.4?(3) and 44.1?(3)° with the benzene rings. In the crystal, mol-ecules are linked by inter-molecular O-H?N and C-H?O hydrogen bonds and C-H?? inter-actions into layers parallel to the bc plane.

PROVIDER: S-EPMC3120371 | BioStudies | 2011-01-01T00:00:00Z

REPOSITORIES: biostudies

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