Unknown

Dataset Information

0

Novel gastric helicobacters and oral campylobacters are present in captive and wild cetaceans.


ABSTRACT: The mammalian gastric and oral mucosa may be colonized by mixed Helicobacter and Campylobacter species, respectively, in individual animals. To better characterize the presence and distribution of Helicobacter and Campylobacter among marine mammals, we used PCR and 16S rDNA sequence analysis to examine gastric and oral samples from ten dolphins (Tursiops gephyreus), one killer whale (Orcinus orca), one false killer whale (Pseudorca crassidens), and three wild La Plata river dolphins (Pontoporia blainvillei). Helicobacter spp. DNA was widely distributed in gastric and oral samples from both captive and wild cetaceans. Phylogenetic analysis demonstrated two Helicobacter sequence clusters, one closely related to H. cetorum, a species isolated from dolphins and whales in North America. The second related cluster was to sequences obtained from dolphins in Australia and to gastric non-H. pylori helicobacters, and may represent a novel taxonomic group. Dental plaque sequences from four dolphins formed a third cluster within the Campylobacter genus that likely represents a novel species isolated from marine mammals. Identification of identical Helicobacter spp. DNA sequences from dental plaque, saliva and gastric fluids from the same hosts, suggests that the oral cavity may be involved in transmission. These results demonstrate that Helicobacter and Campylobacter species are commonly distributed in marine mammals, and identify taxonomic clusters that may represent novel species.

SUBMITTER: Goldman CG 

PROVIDER: S-EPMC3142288 | BioStudies | 2011-01-01

REPOSITORIES: biostudies

Similar Datasets

2002-01-01 | S-EPMC154630 | BioStudies
2013-01-01 | S-EPMC4063339 | BioStudies
2018-01-01 | S-EPMC6154992 | BioStudies
2017-01-01 | S-EPMC5681658 | BioStudies
2013-01-01 | S-EPMC3866246 | BioStudies
2019-01-01 | S-EPMC6425031 | BioStudies
2019-01-01 | S-EPMC6612419 | BioStudies
2016-01-01 | S-EPMC5036180 | BioStudies
2019-01-01 | S-EPMC6530492 | BioStudies
1000-01-01 | S-EPMC1828825 | BioStudies