Dataset Information


A Five-year Review on the Etiology and Antimicrobial Susceptibility Pattern of Otitis Media Pathogens in Jordanian Children.

ABSTRACT: OBJECTIVE: This study aimed to identify the bacteriological agents of otitis media in Jordanian children and to assess the in vitro susceptibility of these isolates to commonly used antibiotics. METHODS: Retrospective analysis of consecutive samples submitted for microbiological evaluation from outpatients children aged between 6 months and 15 years who were clinically diagnosed with otitis media and were treated at Princess Rahma Hospital in North Jordan between January 2005 and December 2009. RESULTS: A total of 724 isolates were recovered from cultures obtained from 863 children patients giving an isolation rate of 83.8%. The male and female isolate ratio was (1.26:1.0). The most common bacterial species isolated were S. aureus (59.9%) followed by Streptococcus pneumoniae (22.4%), Pseudomonas (7.7%), E. coli (5.9%), Klebsiella spp. (3.1%) and Proteus spp. (0.9%). The most of S. aureus isolates were susceptible to vancomycin (94.0%) and gentamicin (87.3%). Streptococcus organisms were susceptible in highest percentage to amoxicillin-clavulanic acid (87.1%). Gram-negative isolates were highly susceptible to ciprofloxacin (83.5%) and gentamicin (79.8%). Among all isolates, vancomycin was the most effective antimicrobial agent with susceptibility rate of 83.9%, whereas cefixime showed the lowest susceptibility rate of 39.7%. CONCLUSIONS: S. aureus isolates were the most frequent bacteria isolated from otitis media and were highly sensitive to vancomycin and gentamicin, while gram-negative isolates were more sensitive to ciprofloxacin and gentamicin.


PROVIDER: S-EPMC3472576 | BioStudies | 2012-01-01

SECONDARY ACCESSION(S): 10.5001/omj.2012.91

REPOSITORIES: biostudies

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