Dataset Information


A Microbial Metagenome (Leucobacter sp.) in Caenorhabditis Whole Genome Sequences.

ABSTRACT: DNA of apparently recent bacterial origin is found in the genomic sequences of Caenorhabditis angaria and Caenorhabditis remanei. Here we present evidence that the DNA belongs to a single species of the genus Leucobacter (high-GC Gram+ Actinobacteria). Metagenomic tools enabled the assembly of the contaminating sequences in a draft genome of 3.2 Mb harboring 2,826 genes. This information provides insight into a microbial organism intimately associated with Caenorhabditis as well as a solid basis for the reassignment of 3,373 metazoan entries of the public database to a novel bacterial species (Leucobacter sp. AEAR). The application of metagenomic techniques can thus prevent annotation errors and reveal unexpected genetic information in data obtained by conventional genomics.

SUBMITTER: Percudani R 

PROVIDER: S-EPMC3583267 | BioStudies | 2013-01-01

REPOSITORIES: biostudies

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