Unknown

Dataset Information

0

Oxygenated Cembranoids from the Soft Coral Sinularia flexibilis.


ABSTRACT: Chemical examination of the Taiwanese soft coral Sinularia flexibilis led to the isolation of five cembrane-based diterpenoids 1-5, including two new metabolites, 11-acetylsinuflexolide (1) and 11-acetyldihydrosinuflexolide (2). The structures of the new metabolites were determined based on extensive spectroscopic analysis, particularly mass spectrometry and 2D NMR (1H-1H COSY, HMQC, HMBC, and NOESY) spectroscopy. Metabolites 1, 3 and 4 exhibited moderate to weak cytotoxicity to human tumor cell lines, HeLa, HEp-2, MCF-7 and MDA-MB-231.

SUBMITTER: Su CC 

PROVIDER: S-EPMC3588100 | BioStudies | 2013-01-01T00:00:00Z

REPOSITORIES: biostudies

Similar Datasets

2012-01-01 | S-EPMC6268420 | BioStudies
1000-01-01 | S-EPMC4071581 | BioStudies
2016-01-01 | S-EPMC4782107 | BioStudies
1000-01-01 | S-EPMC3475270 | BioStudies
1000-01-01 | S-EPMC6117644 | BioStudies
1000-01-01 | S-EPMC4999911 | BioStudies
2016-01-01 | S-EPMC6274415 | BioStudies
2018-01-01 | S-EPMC5923386 | BioStudies
| PRJNA172548 | ENA
1000-01-01 | S-EPMC3677396 | BioStudies