Unknown

Dataset Information

0

Draft Genome Sequence of Escherichia coli Strain Nissle 1917 (Serovar O6:K5:H1).


ABSTRACT: We announce the availability of the 5.023-Mbp high-quality draft assembly of the Escherichia coli strain Nissle 1917 (serovar O6:K5:H1) genome. Short genomic segments from this important probiotic strain have been available in public databases, but the full genome sequence has remained inaccessible. Thus, high-coverage, whole genome sequencing of E. coli Nissle 1917 is presented herein. Reannotation and metabolic reconstruction will enable comparative genomics analysis and model-guided predictions of genetic manipulations leading to increased production of the K5 capsular polysaccharide known as N-acetyl heparosan, a precursor to the anticoagulant pharmaceutical heparin.

SUBMITTER: Cress BF 

PROVIDER: S-EPMC3593317 | BioStudies | 2013-01-01

REPOSITORIES: biostudies

Similar Datasets

2002-01-01 | S-EPMC135379 | BioStudies
2004-01-01 | S-EPMC490877 | BioStudies
2015-01-01 | S-EPMC4366286 | BioStudies
2019-01-01 | S-EPMC6895014 | BioStudies
2005-03-02 | GSE2232 | GEO
1000-01-01 | S-EPMC3495787 | BioStudies
1999-01-01 | S-EPMC94203 | BioStudies
2005-01-01 | S-EPMC1326229 | BioStudies
2008-06-12 | E-GEOD-2232 | ArrayExpress
2020-01-01 | S-EPMC7111071 | BioStudies