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Isolation and structural elucidation of chondrosterins F-H from the marine fungus Chondrostereum sp.


ABSTRACT: The marine fungus Chondrostereum sp. was collected from a soft coral of the species Sarcophyton tortuosum from the South China Sea. Three new compounds, chondrosterins F-H (1, 4 and 5), together with three known compounds, incarnal (2), arthrosporone (3), and (2E)-decene-4,6,8-triyn-1-ol (6), were isolated. Their structures were elucidated primarily based on NMR and MS data. Incarnal (2) exhibited potent cytotoxic activity against various cancer cell lines.

PROVIDER: S-EPMC3640397 | BioStudies |

REPOSITORIES: biostudies

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