Unknown

Dataset Information

0

The RpfC (Rv1884) atomic structure shows high structural conservation within the resuscitation-promoting factor catalytic domain.


ABSTRACT: The first structure of the catalytic domain of RpfC (Rv1884), one of the resuscitation-promoting factors (RPFs) from Mycobacterium tuberculosis, is reported. The structure was solved using molecular replacement once the space group had been correctly identified as twinned P21 rather than the apparent C2221 by searching for anomalous scattering sites in P1. The structure displays a very high degree of structural conservation with the previously published structures of the catalytic domains of RpfB (Rv1009) and RpfE (Rv2450). This structural conservation highlights the importance of the versatile domain composition of the RPF family.

SUBMITTER: Chauviac FX 

PROVIDER: S-EPMC4118796 | BioStudies | 2014-01-01

REPOSITORIES: biostudies

Similar Datasets

2014-01-01 | S-EPMC3970898 | BioStudies
2008-01-01 | S-EPMC2229633 | BioStudies
2018-01-01 | S-EPMC6102972 | BioStudies
2013-01-01 | S-EPMC4070687 | BioStudies
1000-01-01 | S-EPMC4159695 | BioStudies
2013-01-01 | S-EPMC3672874 | BioStudies
2014-01-01 | S-EPMC4114240 | BioStudies
1000-01-01 | S-EPMC6009663 | BioStudies
2013-01-01 | S-EPMC4174818 | BioStudies
1000-01-01 | S-EPMC4325095 | BioStudies