Dataset Information


Pain at multiple body sites and health-related quality of life in older adults: results from the North Staffordshire Osteoarthritis Project.



Number of pain sites (NPS) is a potentially important marker of health-related quality of life (HRQoL) but remains unexplored in older people. This cross-sectional study investigated whether, in older people including the oldest old, NPS was independently associated with poorer mental and physical HRQoL and if the association was moderated by age.


A postal questionnaire sent to a population sample of adults aged ?50 years in North Staffordshire, UK, included the 12-item Short Form Health Survey (SF-12) mental component summary (MCS) and physical component summary (PCS), a blank body pain manikin, socio-demographic, health behaviour and morbidity questions. Participants shaded sites of pain lasting ?1 day in the past 4 weeks on the manikin. OA consultation data were obtained for participants consenting to medical records review.


A total of 13 986 individuals (adjusted response 70.6%) completed a questionnaire, of which 12 408 provided complete pain data. The median NPS reported was 4 [interquartile range (IQR) 0-8]. General linear models showed that an increasing NPS was significantly associated with poorer MCS (? = -0.43, 95% CI -0.46, -0.40) and PCS (? = -0.87, 95% CI -0.90, -0.84). Adjustment for covariates attenuated the associations but they remained significant (


? = -0.28, 95% CI -0.31, -0.24; PCS: ? = -0.63, 95% CI -0.66, -0.59). The association between NPS and MCS or PCS was moderated by age, but the strongest associations were not in the oldest old.


NPS appears to be a potentially modifiable target for improving physical and mental HRQoL in older people. Future analyses should investigate the influence of NPS on HRQoL over time in older people.


PROVIDER: S-EPMC4202023 | BioStudies | 2014-01-01

REPOSITORIES: biostudies

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