Unknown

Dataset Information

0

Livestock-associated MRSA in household members of pig farmers: transmission and dynamics of carriage, a prospective cohort study.


ABSTRACT: This prospective cohort study describes carriage of livestock-associated methicillin-resistant Staphylococcus aureus (LA-MRSA) in household members from 49 farrowing pig farms in the Netherlands (2010-2011). Of 171 household members, 4% were persistent MRSA nasal carriers, and the MRSA prevalence on any given sampling moment was 10% (range 7-11%). Working in the stables (of which 98% was MRSA-positive, prevalence ratio (PR) = 2.11 per 10 hours), working with sows (PR=1.97), and living with an MRSA-positive pig farmer (PR=4.63) were significant determinants for MRSA carriage. Significant protective factors were carriage of methicillin-susceptible Staphylococcus aureus (MSSA) (PR=0.50), and wearing a facemask when working in the stables (37% decreased prevalence). All MRSA strains during the study period were known livestock-associated types. The bacteriophage ?3 was not found in household members. Transmission from pigs and the environment appeared to be important determinants; human-to-human transmission could not sufficiently be differentiated. Wearing a facemask when working in the stables and carriage of MSSA are potential interventional targets.

SUBMITTER: van Cleef BA 

PROVIDER: S-EPMC4436301 | BioStudies | 2015-01-01

REPOSITORIES: biostudies

Similar Datasets

2015-01-01 | S-EPMC4583260 | BioStudies
2017-01-01 | S-EPMC5444836 | BioStudies
2010-01-01 | S-EPMC2953128 | BioStudies
2016-01-01 | S-EPMC5112983 | BioStudies
2013-01-01 | S-EPMC3867410 | BioStudies
1000-01-01 | S-EPMC4107749 | BioStudies
2017-01-01 | S-EPMC5648716 | BioStudies
2020-01-01 | S-EPMC7601186 | BioStudies
2014-01-01 | S-EPMC5824647 | BioStudies
2019-01-01 | S-EPMC6889221 | BioStudies