Unknown

Dataset Information

0

Risk and outcome after ablation of isthmus-dependent atrial flutter in elderly patients.


ABSTRACT: To study the influence of age on the clinical presentation and long-term outcome of patients referred for atrial flutter (AFL) ablation. Age-related differences have been reported regarding the prognosis of arrhythmias.A total of 1187 patients with a mean age 65±12 years consecutively referred for AFL ablation were retrospectively analyzed in the study.445 (37.5%) patients were aged ≥70 (range 70 to 93) among which 345 were aged 70 to 79 years (29.1%) and 100 were aged ≥80 (8.4%). In multivariable analysis, AFL-related rhythmic cardiomyopathy and presentation with 1/1 AFL were less frequent (respectively adjusted OR = 0.44, 0.27-0.74, p = 0.002 and adjusted OR = 0.29, 0.16-0.52, p<0.0001). AFL ablation-related major complications were more frequent in patients ≥70 although remained lower than 10% (7.4% in ≥70 vs. 4.2% in <70, adjusted OR = 1.74, 1.04-2.89, p = 0.03). After 2.1±2.7 years, AFL recurrence was less frequent in patients ≥70 (adjusted OR = 0.54, 0.37-0.80, p = 0.002) whereas atrial fibrillation (AF) occurrence was as frequent in the 70-79 and ≥80 age subsets. As expected, cardiac mortality was higher in older patients. Patients aged ≥80 also had a low probability of AFL recurrence (5.0%) and AF onset (19.0%).Older patients represent 37.5% of patients referred for AFL ablation and displayed a <10% risk of ablation-related complications. Importantly, AFL recurrences were less frequent in patients ≥70 while AF occurrence was as frequent as in patients <70. Similar observations were made in patients ≥80 years. AFL ablation appears to be safe and efficient and should not be ruled out in elderly patients.

PROVIDER: S-EPMC4441372 | BioStudies | 2015-01-01

REPOSITORIES: biostudies

Similar Datasets

| S-EPMC3947706 | BioStudies
2008-01-01 | S-EPMC2292477 | BioStudies
| S-EPMC7068068 | BioStudies
| S-EPMC6486838 | BioStudies
| S-EPMC8632865 | BioStudies
| S-EPMC7303549 | BioStudies
| S-EPMC8632776 | BioStudies
| S-EPMC6549656 | BioStudies
| S-EPMC8134292 | BioStudies
| S-EPMC7779821 | BioStudies