Unknown

Dataset Information

0

Structural Characterization of Neutral Glycosphingolipids from 3T3-L1 Adipocytes.


ABSTRACT: In recent years, obesity has been considered a pathological stage of early lifestyle-related diseases, and adipose tissue and adipocyte research has been active. Glycosphingolipids are involved in the pathogenesis of type 2 diabetes induced by insulin resistance, but the details of the glycosphingolipid molecular species composition of adipocytes have yet to be elucidated. We used 3T3-L1 adipocytes and the 1,2-dichloroethane-wash method to remove triacylglycerols, which are abundant in adipocytes, and analyzed the structures of glycosphingolipids, particularly neutral glycosphingolipids, using liquid chromatography-mass spectrometry.

SUBMITTER: Kojima H 

PROVIDER: S-EPMC4541715 | BioStudies | 2015-01-01T00:00:00Z

REPOSITORIES: biostudies

Similar Datasets

1980-01-01 | S-EPMC1162018 | BioStudies
1979-01-01 | S-EPMC1186610 | BioStudies
1989-01-01 | S-EPMC1138328 | BioStudies
2020-01-01 | S-EPMC7568394 | BioStudies
2020-01-01 | S-EPMC7653041 | BioStudies
2013-01-01 | S-EPMC3549955 | BioStudies
1978-01-01 | S-EPMC1185825 | BioStudies
2010-01-01 | S-EPMC2838997 | BioStudies
2016-01-01 | S-EPMC5560440 | BioStudies
2020-01-01 | S-EPMC7232171 | BioStudies