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Transmission of Middle East Respiratory Syndrome Coronavirus Infections in Healthcare Settings, Abu Dhabi.


ABSTRACT: Middle East respiratory syndrome coronavirus (MERS-CoV) infections sharply increased in the Arabian Peninsula during spring 2014. In Abu Dhabi, United Arab Emirates, these infections occurred primarily among healthcare workers and patients. To identify and describe epidemiologic and clinical characteristics of persons with healthcare-associated infection, we reviewed laboratory-confirmed MERS-CoV cases reported to the Health Authority of Abu Dhabi during January 1, 2013-May 9, 2014. Of 65 case-patients identified with MERS-CoV infection, 27 (42%) had healthcare-associated cases. Epidemiologic and genetic sequencing findings suggest that 3 healthcare clusters of MERS-CoV infection occurred, including 1 that resulted in 20 infected persons in 1 hospital. MERS-CoV in healthcare settings spread predominantly before MERS-CoV infection was diagnosed, underscoring the importance of increasing awareness and infection control measures at first points of entry to healthcare facilities.

SUBMITTER: Hunter JC 

PROVIDER: S-EPMC4806977 | BioStudies | 2016-01-01

SECONDARY ACCESSION(S): 10.2807/1560-7917.ES2015.20.25.21163

REPOSITORIES: biostudies

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Publications

Preliminary epidemiological assessment of MERS-CoV outbreak in South Korea, May to June 2015.

Cowling B J BJ   Park M M   Fang V J VJ   Wu P P   Leung G M GM   Wu J T JT  

Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin 20150625 25


South Korea is experiencing the largest outbreak of Middle East respiratory syndrome coronavirus infections outside the Arabian Peninsula, with 166 laboratory-confirmed cases, including 24 deaths up to 19 June 2015. We estimated that the mean incubation period was 6.7 days and the mean serial interval 12.6 days. We found it unlikely that infectiousness precedes symptom onset. Based on currently available data, we predict an overall case fatality risk of 21% (95% credible interval: 14–31). ...[more]

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