Dataset Information


A natural odor attraction between lactic acid bacteria and the nematode Caenorhabditis elegans.

ABSTRACT: Animal predators can track prey using their keen sense of smell. The bacteriovorous nematode Caenorhabditis elegans employs sensitive olfactory sensory neurons that express vertebrate-like odor receptors to locate bacteria. C. elegans displays odor-related behaviors such as attraction, aversion and adaptation, but the ecological significance of these behaviors is not known. Using a combination of food microbiology and genetics, we elucidate a possible predator-prey relationship between C. elegans and lactic acid bacteria (LAB) in rotting citrus fruit. LAB produces the volatile odor diacetyl as an oxidized by-product of fermentation in the presence of citrate. We show that C. elegans is attracted to LAB when grown on citrate media or Citrus medica L, commonly known as yuzu, a citrus fruit native to East Asia, and this attraction is mediated by the diacetyl odor receptor, ODR-10. We isolated a wild LAB strain and a wild C. elegans-related nematode from rotten yuzu, and demonstrate that the wild nematode was attracted to the diacetyl produced by LAB. These results not only identify an ecological function for a C. elegans olfactory behavior, but contribute to the growing understanding of ecological relationships between the microbial and metazoan worlds.

PROVIDER: S-EPMC4817685 | BioStudies |

REPOSITORIES: biostudies

Similar Datasets

| S-EPMC5045890 | BioStudies
| S-EPMC7811839 | BioStudies
| S-EPMC3931561 | BioStudies
| S-EPMC6018680 | BioStudies
| S-EPMC7392509 | BioStudies
| S-EPMC7662486 | BioStudies
| S-EPMC4209970 | BioStudies
| S-EPMC5220224 | BioStudies
| S-EPMC7874617 | BioStudies
| S-EPMC2586605 | BioStudies