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Revealing human intestinal stem cell and crypt dynamics.


ABSTRACT: Stem cell and crypt dynamics in the human gut have been remarkably poorly characterized. We used random somatic mutations to trace stem cell lineages in the human intestine and coupled these data with mathematical modeling to infer the in vivo temporal dynamics of human intestinal stem cells.

SUBMITTER: Baker AM 

PROVIDER: S-EPMC4904973 | BioStudies | 2014-01-01

SECONDARY ACCESSION(S): 10.4161/23723548.2014.970069

REPOSITORIES: biostudies

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