Unknown

Dataset Information

0

The BARD1/HP1 interaction: Another clue to heterochromatin involvement in homologous recombination.


ABSTRACT: Chromatin compaction represents a barrier for the repair of DNA double-strand breaks (DSBs). However, heterochromatin components are also required for DSB repair by homologous recombination. The BARD1/HP1 interaction, required for the retention of BRCA1, CTIP, and RAD51 at DSB sites, may play a critical role in the crosstalk between chromatin compaction and DSB repair.

SUBMITTER: Fukuda T 

PROVIDER: S-EPMC4905335 | BioStudies | 2016-01-01

SECONDARY ACCESSION(S): 10.1080/23723556.2015.1030535

REPOSITORIES: biostudies

Similar Datasets

2015-01-01 | S-EPMC5003120 | BioStudies
1000-01-01 | S-EPMC5084677 | BioStudies
2016-01-01 | S-EPMC6522385 | BioStudies
2013-01-01 | S-EPMC3664841 | BioStudies
1000-01-01 | S-EPMC3061033 | BioStudies
2019-01-01 | S-EPMC6420097 | BioStudies
1000-01-01 | S-EPMC4274264 | BioStudies
2017-01-01 | S-EPMC5800781 | BioStudies
1000-01-01 | S-EPMC5389477 | BioStudies
1000-01-01 | S-EPMC3664708 | BioStudies