Dataset Information


Targeting Head and Neck Cancer Stem Cells: Current Advances and Future Challenges.

ABSTRACT: Cancer stem cells (CSCs), or tumor-initiating cells, comprise a subset of tumor cells with demonstrated ability for tumor growth, invasion, metastasis, and resistance to chemotherapy and radiation. Targeting of CSCs remains an attractive yet elusive therapeutic option, with the goal of increasing specificity and effectiveness in tumor eradication, as well as decreasing off-target or systemic toxicity. Research into further characterization and targeted therapy toward head and neck CSCs is an active and rapidly evolving field. This review discusses the current state of research into therapy against head and neck CSCs and future directions for targeted therapy.

SUBMITTER: Birkeland AC 

PROVIDER: S-EPMC5469447 | BioStudies | 2015-01-01

REPOSITORIES: biostudies

Similar Datasets

2020-01-01 | S-EPMC7137421 | BioStudies
1000-01-01 | S-EPMC4747200 | BioStudies
2020-01-01 | S-EPMC7024642 | BioStudies
2014-01-01 | S-EPMC3918396 | BioStudies
2015-01-01 | S-EPMC4295111 | BioStudies
2017-01-01 | S-EPMC5400558 | BioStudies
2020-01-01 | S-EPMC7056512 | BioStudies
2019-01-01 | S-EPMC6562868 | BioStudies
2016-01-01 | S-EPMC4724810 | BioStudies
2020-01-01 | S-EPMC7464411 | BioStudies