Unknown

Dataset Information

0

Duct-to-mucosa versus invagination pancreaticojejunostomy after pancreaticoduodenectomy: a meta-analysis.


ABSTRACT: We aimed to compare the two most commonly used pancreatico-jejunostomy reconstruction techniques-duct-to-mucosa and invagination.Databases, including MEDLINE, EMBASE, Cochrane Library, and several clinical trial registration centers were searched. Randomized controlled trials that compared duct-to-mucosa and invagination pancreaticojejunostomy techniques after pancreaticoduodenectomy were included and analyzed.In total, seven RCTs were included, involving 850 patients. The difference in postoperative pancreatic fistula rate between the duct-to-mucosa and invagination pancreaticojejunostomy was not significant (RR = 1.03, 95% CI = 0.76-1.39, P = 0.86). There was no significant difference in clinically relevant postoperative pancreatic fistula between the two groups (RR = 0.78, 95% CI = 0.15-3.96, P = 0.77). The overall morbidity, overall mortality, delayed gastric emptying, intra-abdominal collection, reoperation rate, and length of hospital stay between the two groups were not significantly different. Sensitivity analysis showed that the meta-analysis was stable. Further, no significant publication bias was seen.Duct-to-mucosa and invagination pancreaticojejunostomy techniques after pancreaticoduodenectomy were comparable in terms of postoperative pancreatic fistula incidence and other parameters.

PROVIDER: S-EPMC5542280 | BioStudies | 2017-01-01

REPOSITORIES: biostudies

Similar Datasets

2013-01-01 | S-EPMC3691567 | BioStudies
| S-EPMC7105835 | BioStudies
2016-01-01 | S-EPMC4988010 | BioStudies
2019-01-01 | S-EPMC6629351 | BioStudies
2020-01-01 | S-EPMC7310108 | BioStudies
2015-01-01 | S-EPMC4447507 | BioStudies
| S-EPMC7578105 | BioStudies
2019-01-01 | S-EPMC6325750 | BioStudies
2008-01-01 | S-EPMC2504855 | BioStudies
2018-01-01 | S-EPMC6136772 | BioStudies