Unknown

Dataset Information

0

Synthesis of trifluoromethylated 2H-azirines through Togni reagent-mediated trifluoromethylation followed by PhIO-mediated azirination.


ABSTRACT: The reaction of enamine compounds with the Togni reagent in the presence of CuI afforded ?-trifluoromethylated enamine intermediates, which were converted directly to biologically interesting trifluoromethylated 2H-azirines by an iodosobenzene (PhIO)-mediated intramolecular azirination in a one-pot process.

SUBMITTER: Sun J 

PROVIDER: S-EPMC6009194 | BioStudies | 2018-01-01T00:00:00Z

REPOSITORIES: biostudies

Similar Datasets

2018-01-01 | S-EPMC6876689 | BioStudies
2013-01-01 | S-EPMC3886853 | BioStudies
1000-01-01 | S-EPMC6296300 | BioStudies
1000-01-01 | S-EPMC5727777 | BioStudies
2019-01-01 | S-EPMC6461707 | BioStudies
2012-01-01 | S-EPMC3475161 | BioStudies
1000-01-01 | S-EPMC4362021 | BioStudies
1000-01-01 | S-EPMC3999847 | BioStudies
2013-01-01 | S-EPMC3904770 | BioStudies
2017-01-01 | S-EPMC5505263 | BioStudies