Unknown

Dataset Information

0

Comparative effectiveness of bariatric procedures among adolescents: the PCORnet bariatric study.


ABSTRACT: BACKGROUND:Bariatric surgery has been used for treatment of severe obesity in adolescents but most studies have been small and limited in follow-up. OBJECTIVES:We hypothesized that electronic health record data could be used to compare effectiveness of bariatric procedures in adolescents. SETTING:Data were obtained from clinical research networks using a common data model to extract data from each site. METHODS:Adolescents who underwent a primary bariatric procedure from 2005 through 2015 were identified. The percent change in body mass index (BMI) at 1, 3, and 5 years was estimated using random effects linear regression for patients undergoing all operations. Propensity score adjusted estimates and 95% confidence intervals were estimated for procedures with >25 patients at each time period. RESULTS:This cohort of 544 adolescents was predominantly female (79%) and White (66%), with mean (±standard deviation) age of 17.3 (±1.6) years and mean BMI of 49.8 (± 7.8) kg/m2. Procedures included Roux-en-Y gastric bypass (RYGB; n?=?177), sleeve gastrectomy (SG; n?=?306), and laparoscopic adjustable gastric banding (n?=?61). For those undergoing RYGB, SG, and laparoscopic adjustable gastric banding, mean (95% confidence interval) BMI changes of -31% (-30% to -33%), -28% (-27% to -29%), and -10% (-8% to -12%), were estimated at 1 year. For RYGB and SG, BMI changes of -29% (-26% to -33%) and -25% (-22% to -28%) were estimated at 3 years. CONCLUSIONS:Adolescents undergoing SG and RYGB experienced greater declines in BMI at 1- and 3-year follow-up time points, while laparoscopic adjustable gastric banding was significantly less effective for BMI reduction.

SUBMITTER: Inge TH 

PROVIDER: S-EPMC6165694 | BioStudies | 2018-01-01

REPOSITORIES: biostudies

Similar Datasets

1000-01-01 | S-EPMC5704829 | BioStudies
2018-01-01 | S-EPMC6652193 | BioStudies
2017-01-01 | S-EPMC5473622 | BioStudies
2019-01-01 | S-EPMC6350363 | BioStudies
2018-01-01 | S-EPMC6817973 | BioStudies
2014-01-01 | S-EPMC5041303 | BioStudies
2016-01-01 | S-EPMC5112115 | BioStudies
2015-01-01 | S-EPMC4512927 | BioStudies
2013-01-01 | S-EPMC3955952 | BioStudies
1000-01-01 | S-EPMC5219637 | BioStudies