Unknown

Dataset Information

0

Squalene emulsions for parenteral vaccine and drug delivery.


ABSTRACT: Squalene is a linear triterpene that is extensively utilized as a principal component of parenteral emulsions for drug and vaccine delivery. In this review, the chemical structure and sources of squalene are presented. Moreover, the physicochemical and biological properties of squalene-containing emulsions are evaluated in the context of parenteral formulations. Historical and current parenteral emulsion products containing squalene or squalane are discussed. The safety of squalene-based products is also addressed. Finally, analytical techniques for characterization of squalene emulsions are examined.

SUBMITTER: Fox CB 

PROVIDER: S-EPMC6254918 | BioStudies | 2009-01-01T00:00:00Z

SECONDARY ACCESSION(S): NCT00702221

REPOSITORIES: biostudies

Similar Datasets

2011-01-01 | S-EPMC3224191 | BioStudies
1000-01-01 | S-EPMC3364393 | BioStudies
2019-01-01 | S-EPMC6622470 | BioStudies
2014-01-01 | S-EPMC4264955 | BioStudies
2016-01-01 | S-EPMC4686677 | BioStudies
2015-01-01 | S-EPMC4586530 | BioStudies
2017-01-01 | S-EPMC5678165 | BioStudies
2014-01-01 | S-EPMC4464759 | BioStudies
2018-01-01 | S-EPMC6249010 | BioStudies
2014-01-01 | S-EPMC3934731 | BioStudies