Unknown

Dataset Information

0

?-Selective Glycosylation with ?-Glycosyl Sulfonium Ions Prepared via Intramolecular Alkylation.


ABSTRACT: Stereoselective glycosylation remains the main challenge in the chemical synthesis of oligosaccharides. Herein we report a simple method to convert thioglycosides into ?-sulfonium ions via an intramolecular alkylation reaction, leading to highly ?-selective glycosylations for a variety of glycosyl acceptors. The influence of the thioglycoside substituent and the protecting group pattern on the glycosyl donor was investigated and showed a clear correlation with the observed stereoselectivity.

PROVIDER: S-EPMC6454400 | BioStudies |

REPOSITORIES: biostudies

Similar Datasets

| S-EPMC3104671 | BioStudies
| S-EPMC3353542 | BioStudies
| S-EPMC8111381 | BioStudies
| S-EPMC5078750 | BioStudies
2013-01-01 | S-EPMC3678522 | BioStudies
| S-EPMC2533432 | BioStudies
| S-EPMC4273275 | BioStudies
| S-EPMC6742554 | BioStudies
| S-EPMC4658653 | BioStudies
| S-EPMC3436940 | BioStudies