Ontology highlight
ABSTRACT:
SUBMITTER: van Loben Sels JM
PROVIDER: S-EPMC6563215 | BioStudies | 2019-01-01
SECONDARY ACCESSION(S): 10.12688/wellcomeopenres.11300.1
REPOSITORIES: biostudies
Cutler Antony J AJ Oliveira Joao J Ferreira Ricardo C RC Challis Ben B Walker Neil M NM Caddy Sarah S Lu Jia J Stevens Helen E HE Smyth Deborah J DJ Pekalski Marcin L ML Kennet Jane J Hunter Kara M D KMD Goodfellow Ian I Wicker Linda S LS Todd John A JA Waldron-Lynch Frank F
Wellcome open research 20171005
<h4>Background</h4>The infection of a participant with norovirus during the adaptive study of interleukin-2 dose on regulatory T cells in type 1 diabetes (DILT1D) allowed a detailed insight into the cellular and cytokine immune responses to this prevalent gastrointestinal pathogen.<h4>Methods</h4>Serial blood, serum and peripheral blood mononuclear cell (PBMC) samples were collected pre-, and post-development of the infection. To differentiate between the immune response to norovirus and to cont ...[more]