Unknown

Dataset Information

0

Sequence assignment for low-resolution modelling of protein crystal structures.


ABSTRACT: The performance of automated model building in crystal structure determination usually decreases with the resolution of the experimental data, and may result in fragmented models and incorrect side-chain assignment. Presented here are new methods for machine-learning-based docking of main-chain fragments to the sequence and for their sequence-independent connection using a dedicated library of protein fragments. The combined use of these new methods noticeably increases sequence coverage and reduces fragmentation of the protein models automatically built with ARP/wARP.

SUBMITTER: Chojnowski G 

PROVIDER: S-EPMC6677015 | BioStudies | 2019-01-01

SECONDARY ACCESSION(S): 2ydx

REPOSITORIES: biostudies

Similar Datasets

2020-01-01 | S-EPMC7057216 | BioStudies
2008-01-01 | S-EPMC2582149 | BioStudies
2007-01-01 | S-EPMC2483501 | BioStudies
2018-01-01 | S-EPMC5947761 | BioStudies
2008-01-01 | S-EPMC2394809 | BioStudies
2001-01-01 | S-EPMC3691023 | BioStudies
2012-01-01 | S-EPMC3274391 | BioStudies
2007-01-01 | S-EPMC2567142 | BioStudies
1992-01-01 | S-EPMC1131994 | BioStudies
2013-01-01 | S-EPMC3606041 | BioStudies