Unknown

Dataset Information

0

?-Emitters for Radiotherapy: From Basic Radiochemistry to Clinical Studies-Part 2.


ABSTRACT: The use of radioactive sources to deliver cytotoxic ionizing radiation to disease sites dates back to the early 20th century, with the discovery of radium and its physiologic effects. ?-emitters are of particular interest in the field of clinical oncology for radiotherapy applications. The first part of this review explored the basic radiochemistry, high cell-killing potency, and availability of ?-emitting radionuclides, together with hurdles such as radiolabeling methods and daughter redistribution. The second part of this review will give an overview of the most promising and current uses of ?-emitters in preclinical and clinical studies.

SUBMITTER: Poty S 

PROVIDER: S-EPMC6910645 | BioStudies | 2018-01-01

REPOSITORIES: biostudies

Similar Datasets

1000-01-01 | S-EPMC5193009 | BioStudies
1000-01-01 | S-EPMC6211253 | BioStudies
2019-01-01 | S-EPMC6617999 | BioStudies
1000-01-01 | S-EPMC5433050 | BioStudies
2019-01-01 | S-EPMC6495241 | BioStudies
2018-01-01 | S-EPMC6043743 | BioStudies
2020-01-01 | S-EPMC7256013 | BioStudies
1000-01-01 | S-EPMC5233741 | BioStudies
2018-01-01 | S-EPMC6099343 | BioStudies
2020-01-01 | S-EPMC7070971 | BioStudies