Unknown

Dataset Information

0

Cupredoxins--a study of how proteins may evolve to use metals for bioenergetic processes.


ABSTRACT: Cupredoxins are small proteins that contain type I copper centers, which are ubiquitous in nature. They function as electron transfer shuttles between proteins. This review of the structure and properties of native cupredoxins, and those modified by site-directed mutagenesis, illustrates how these proteins may have evolved to specifically bind copper, develop recognition sites for specific redox partners, tune redox potential for a particular function, and allow for efficient electron transfer through the protein matrix. This is relevant to the general understanding of the roles of metals in energy metabolism, respiration and photosynthesis.

SUBMITTER: Choi M 

PROVIDER: S-EPMC6916721 | BioStudies | 2011-01-01

REPOSITORIES: biostudies

Similar Datasets

1000-01-01 | S-EPMC2143285 | BioStudies
2014-01-01 | S-EPMC4059628 | BioStudies
2016-01-01 | S-EPMC5110120 | BioStudies
2012-01-01 | S-EPMC3386083 | BioStudies
2018-01-01 | S-EPMC6183058 | BioStudies
2009-01-01 | S-EPMC2666997 | BioStudies
2020-01-01 | S-EPMC7497095 | BioStudies
1000-01-01 | S-EPMC5968567 | BioStudies
2012-01-01 | S-EPMC3457516 | BioStudies
2016-01-01 | S-EPMC4761536 | BioStudies